Evolution has the Solution
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BIPRESELECT is one of the few existing preselection techniques in early drug development according to physico-chemical properties, e.g. logP, mol weight, solubility
Defining qualified leads at very early stages of your Drug Discovery
NP hit confirmation and hit validation need to be followed by the fast conversion into qualified lead series. Therefore the assessment of physicochemical and pharmacological properties has to be conducted at very early stages of drug discovery for the purpose of accelerating the conversion of hits into leads and then into qualified development candidates.
Bicoll has developed one of the few existing preselection techniques in early drug development
Our high throughput prediction toolbox BIPRESELECT enables reducing the attrition rate of potential drug candidates as they progress through development. To identify and sort out "troublemaker-compounds" up-front to significantly lower your screening costs and increase productivity, the aim is to make the lead compound not only interact with the target, but also have specific ADME/Tox properties - properties that usually require further improvement in the course of Lead Optimization.
The high potency of natural compounds and their proven capability to influence cell metabolism is promoted by data of selected early ADME properties. This will help you to focus development resources on the promising compounds exclusively.
Drug Discovery NP: Lead Generation